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Effect of Chitosan Molecular Weight and Deacetylation Degree on Hemostasis

Effect of Chitosan Molecular Weight and Deacetylation Degree on Hemostasis  

【作者】 Jian Yang; Feng Tian; Zheng Wang  
【作者单位】 Tianjin Institute of Medical Equipment, Tianjin 300161, People's Republic of China  
【关键词】 blood-      material interaction; coagulation; chitosan; molecular weight; deacetylation degree  
【刊名】 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH(PART B)  
【卷期】 vol.84B; no.1  
【出版年】 2008   
【ISSN】 1552-4973  
【期号】 no.1   
【页码】 p.131-137  
【本文页数】 7  
【分类号】 R31  
【正文语种】 eng  
【文 摘】 Comparative studies have been carried out among solid- state chitosan soliquoid, chitosan acetic acid physiological saline solution, and carboxymethyl chitosan
physiological saline solution to discover the hemostatic effect of molecular weight (M_w) and deacetylation
degree (DA) of chitosan. It was found that solid-state chitosan and chitosan acetic acid physiological saline
solution performed different hemostatic mechanisms. When blood mixed with chitosan acetic acid physiological
 saline solution, the eryth...  
【来源】 西文期刊  
【正题名】 Effect of Chitosan Molecular Weight and Deacetylation Degree on Hemostasis  
【期刊名称】 JOURNAL OF BIOMEDICAL MATERIALS RESEARCH(PART B)  
【期刊卷期】 vol.84B  
【期刊年】 2008

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